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open access
ConclusionsPatient selection
An Institutional Review Board approval was obtained from University of Arizona prior to commencing the study. A total of 38 patients were recruited resulting in 56 fallopian tube specimens. In this study, cells from bilateral fallopian tubes were combined into a single vial to generate one specimen for each of 20 patients. The remaining specimens represented samples from a single fallopian tube. Samples from pregnant women were excluded. Patients’ age ranged from 32 to 86 years old with a mean of 55 years, of whom 26 patients were post-menopausal and 12 patients were pre-menopausal. Informed consent was obtained from each patient.
In
summary, this study shows tubal cytology can distinguish malignant from
non-malignant and identify precursor lesions such as STIC. In addition,
tubal cytology may help to identify non-malignant proliferative
disorders. There is potential utility for tubal cytology in screening
women at high risk for ovarian or tubal malignancy prior to bilateral
risk reducing salpingo-oophorectomy.
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