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McGill University
Detecting OVarian cancer Early

If detected early (stage I) ovarian cancer (OC) is curable by surgery alone in over 90% of the cases. Over 70% of women are diagnosed in stage III or IV, when despite extensive surgery and chemotherapy, over 50% will relapse within two years, and more than 80% will die of disease within 5 years.
Objectives:
- To determine whether the presence of a fast tracking open access dedicated diagnostic center will increase the proportion of women diagnosed at early stages where they are curable.
- To inform and educate the public and primary care doctors about the symptoms of ovarian cancer and the appropriate diagnostic investigations
- To develop the probability tool that will accurately identify the particular cluster of symptoms that suggest that the probability of OC is high in a particular symptomatic woman
Women over 50 year-old, symptomatic for more than 2 weeks and less than one year are eligible and no referrals are necessary. They are assessed by physical examination, endovaginal ultrasound and serial blood test, CA-125 to rule in or rule out ovarian cancer.
Funded by: Canadian Institute of Health Research (CIHR), McGill University Health Centre Foundation, Royal Victoria Hospital Foundation and the Montreal General Hospital Foundation
Principal Investigator: Dr Lucy Gilbert (MUHC) profileCo-Investigators: Dr S Krishnamurthy profile, Dr I Karp, Dr M Tremblay, Dr P Gauthier, Dr JSampalis profile, Dr J Takefman profile
Refer women to the DOVE project at 1-866-716-3267 to schedule an appointment for ovarian cancer diagnostic testing.
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