Leptomeningeal metastasis from gynecologic cancers diagnosed by brain MRI Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Thursday, October 06, 2016

Leptomeningeal metastasis from gynecologic cancers diagnosed by brain MRI



Leptomeningeal carcinomatosis (LC) is a rare complication of cancer in which the disease spreads to the membranes (meninges) surrounding the brain and spinal cord. LC occurs in approximately 5% of people with cancer and is usually terminal.
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abstract

 Leptomeningeal metastasis (LM) is rarely observed in gynecologic cancers. As gadolinium-enhanced magnetic resonance imaging (Gd-MRI) is highly effective for diagnosing LM, the aim of this study is to describe the clinical behaviors and outcomes of LM patients who were diagnosed by Gd-MRI. After securing institutional review board approvals, we retrospectively reviewed patient records. Eight patients were found to have LM from gynecological malignancies. Primary tumors included three ovarian, one tubal, one peritoneal, two endometrial, and one cervical cancer. Gd-MRI of the brain and the spine is indicated as the high priority inspection for the diagnosis of this devastating complication.

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