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Two novel sequence variants in MSH2 gene in a patient who underwent cancer genetic counseling for a very early-onset epithelial ovarian cancer | Hereditary Cancer in Clinical Practice | Full Text
Discussion
Cancer
genetic counseling should be always offered during the work-up of young
patients with epithelial ovarian cancer, in order to screen the
presence of a hereditary syndrome and to improve the oncological
follow-up including intensified surveillance. Clinicians should be
particularly careful to the evaluation of a positive family history of
cancer, being ovarian cancer involved in three different syndromes, such
as site-specific, HBOC and Lynch Syndrome.
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