Why most clinical research is not useful - John Ioannidis Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Friday, November 25, 2016

Why most clinical research is not useful - John Ioannidis


It makes no sense to perform clinical research that has no relevance to patient care, so why do we do it, and how can we stop? John Ioannidis ponders the problem and offers some suggestions.
This article first appeared in PLoS Medicine
(doi:10.1371/journal.pmed.1002049), on 21 June 2016,
and is republished here under a creative commons license.
Illustrations are added by Cancer World
 Data show only weak or modest correlations between the amount of research done and the burden of various diseases (5,6). Moreover, disease mongering affects multiple medical specialties (4,7,8).
 Useful clinical research procures a clinically relevant information gain (9): it adds to what we already know. This means that, first, we need to be aware of what we already know so that new information can be placed in context (10).
 Research inferences should be applicable to real-life circumstances.


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