RCTs vs. Observational Studies: Why Not Just Live Together? Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Thursday, December 01, 2016

RCTs vs. Observational Studies: Why Not Just Live Together?


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Although it is important to understand the strengths and limitations of both RCTs (efficacy studies) and observational studies (effectiveness studies), none of the study designs should be considered in isolation since all types of evidence rely primarily on the rigour with which individual studies were conducted (regardless of the methodological approach) and the care with which they are interpreted.[19] Interpretation of the results obtained from both RCTs and observational studies can help understand the efficacy/effectiveness and safety of a therapeutic option. Meta-analyses using both RCT and observational studies should be used to highlight some questions that neither a RCT, nor an observational study would have the ability to solve by themselves.....


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