(BRCA2) Prostate cancer team cracks genetic code to show why inherited disease can turn lethal Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

Blog Archives: Nov 2004 - present

#ovariancancers



Special items: Ovarian Cancer and Us blog best viewed in Firefox

Search This Blog

Wednesday, January 11, 2017

(BRCA2) Prostate cancer team cracks genetic code to show why inherited disease can turn lethal



CNW Group
(press release)

TORONTO, Jan. 9, 2017 /CNW/ - Canadian and Australian prostate cancer researchers have discovered a key piece in the genetic puzzle of why men born with a BRCA2 mutation may develop aggressive localized cancers that resist treatment and become lethal for up to 50% of patients within five years.
The findings, published online today in Nature Communications, show that BRCA2-associated tumours are already pre-set to be aggressive, even before treatment. This is because the genes normally involved in regulating cell growth and division are abnormal in the BRCA2-associated cancers right from the get-go and therefore are resistant to therapy right up front, says co-principal investigator Dr. Robert Bristow, clinician-scientist at Princess Margaret Cancer Centre, University Health Network. He talks about the research at https://youtu.be/dXlntpaWtaI....

0 comments :

Post a Comment

Your comments?