Case Report: Ductal Carcinoma in situ Detected during Prospective MR Imaging Screening of a Woman with a BRCA2 Mutation (Japan) Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Wednesday, January 18, 2017

Case Report: Ductal Carcinoma in situ Detected during Prospective MR Imaging Screening of a Woman with a BRCA2 Mutation (Japan)



pdf

( Japanese HBOC Con-sortium) They found that HBOC may have nearly the same prevalence in Japan as in the US or Europe. Thus, a nation-wide database of HBOC is thought to be very important for developing risk models for BRCA1/2 carriers in Japan.
 Case Report

A 48-year-old woman presented with no particular chief  complaints and no right nipple discharge.
Family History: Her sister (second daughter) had develped breast cancer at the age of 30 years, another sister (third daughter) also had breast cancer at the age of 36 years
and had tested positive for a BRCA2 mutation, her mother had suffered breast cancer at the age of 53 years, and her mother’s sister (second daughter) also had breast cancer at the age of 52 years and ovarian or uterine cancer at the age of 58 years (Fig. 1).
Past History: No cancer and no particular disease.

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