Comparative effectiveness of screening strategies for colorectal cancer

Blogger's Note: of interest due to the conflicts between the U.S. vs the Canadian recommendations in the general public; also of interest to Lynch Syndrome patients where annual/bi-annual colonoscopies are recommended but for Lynch Syndrome patients who might think to replace colonoscopies with alternative methods of testing

abstract

 This study compares the outcomes of various screening strategies on CRC outcomes.

RESULTS

Colonoscopy emerged as the most effective screening strategy with the highest life years gained and CRCs prevented and the lowest total costs...... Improved sensitivity or specificity of a screening test for CRC detection was not sufficient to close the outcomes gap compared with colonoscopy.