NCI: Engagement with Genetic Information and Uptake of Genetic Testing: the Role of Trust and Personal Cancer History Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Sunday, January 22, 2017

NCI: Engagement with Genetic Information and Uptake of Genetic Testing: the Role of Trust and Personal Cancer History



Engagement with Genetic Information and Uptake of Genetic Testing: the Role of Trust and Personal Cancer History
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 We used national survey data to (1) determine the extent to which individuals trust the sources from which they are most likely to receive information about cancer-related genetic tests (BRCA1/2, Lynch syndrome), (2) examine how level of trust for sources of genetic information might be related to cancer-related genetic testing uptake, and (3) determine whether key factors, such as cancer history and numeracy, moderate the latter association. We used cross-sectional data from the Health Information National Trends Survey.

Our study sample included individuals who responded that they had heard or read about genetic tests (n = 1117). All analyses accounted for complex survey design. Although respondents trusted information from health professionals the most, they were significantly less likely to report hearing about genetic testing from such professionals than via television (p < 0.01). Regardless of source, higher levels of trust in the information source from which participants heard about genetic tests were associated with increased odds of genetic testing uptake, particularly among those with a personal cancer history. Numeracy was not associated with genetic testing uptake. Because health professionals were among the most trusted health information sources, they may serve as important brokers of genetic testing information for those with a personal cancer history.

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