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Ovarian cancer and the immune system
Highlights
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- The immune system is an important player in ovarian cancer behaviour
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- Intratumoral studies of the immune system show an overwhelming immunosuppression
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- The immune signature in the blood can be important as a new biomarker.
Short communication in response to the review of Turner et al. entitled "Ovarian cancer and the immune system - the role of targeted therapies" published in Gynecological Oncology. We believe systemic immune parameters might be a good alternative to tumor biopsy to gain insight in the immunological background of ovarian cancer.
With great interest, we read the review of Turner et al. entitled “Ovarian cancer and the immune system – the role of targeted therapies” published in Gynecological Oncology ( Turner et al., 2016).
The authors intelligibly describe the complexity of the immune system
in cancer in a clinically relevant manner. Novel information concerning
the immune system in cancer is constantly emerging. Currently, there are
several immunotherapy trials, recruiting ovarian cancer patients.
However, selecting the patients who might have the most chance of having
a beneficial effect of immunotherapy is difficult......
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