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Showing posts with label BRCA 1. Show all posts
Showing posts with label BRCA 1. Show all posts
Wednesday, May 16, 2012

DcR3 binds to ovarian cancer via heparan sulfate proteoglycans and modulates tumor cells response to platinum with corresponding alteration in the expression of BRCA1

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DcR3 binds to ovarian cancer via heparan sulfateproteoglycans and modulates tumor cells response toplatinum with corresponding alteration in...
Saturday, May 05, 2012

paywalled: Dosage Effect of BRCA1 and BRCA 2 Mutated Allelic Transcript (French Canadian)

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Dosage Effect of BRCA1/2-Mutated Allelic Transcript : We hypothesized that the transcriptome of primary cultures of morphologically normal...
Sunday, February 20, 2011

Studying Therapy Response and Resistance in Mouse Models for BRCA1-Deficient Breast Cancer

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Wednesday, September 22, 2010

health media: BRCA1 Breast Cancer Risk Linked To Other Genes

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"...People who carry certain mutations of the BRCA1 gene are known to have a higher risk of developing breast cancer. Couch told the ...
Tuesday, August 10, 2010

Objective To identify risk factors for the presence of a non-invasive lesion of the fallopian tube in women with a BRCA1 or BRCA2 mutation (abstract)

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Objective To identify risk factors for the presence of a non-invasive lesion of the fallopian tube in women with a BRCA1 or BRCA2 mutat...
Sunday, July 04, 2010

Risk factors for carcinoma of the fallopian tube in women with and without a germline BRCA mutation

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Reminder on stats: < 1.0 is decreased risk; > 1.0 is increased risk; OR=overall risk; edited some stats for ease of reading - see abs...
Saturday, June 12, 2010

Oral contraceptive use and breast or ovarian cancer risk in BRCA1/2 carriers: A meta-analysis

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CONCLUSIONS: OC users carrying an ascertained BRCA1/2 mutation have a reduced risk of ovarian cancer, proportional to the duration of use. ...
Thursday, June 03, 2010

Comprehensive Analysis of Missense Variations in the BRCT Domain of BRCA 1 by Structural and Functional Assays

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Comprehensive Analysis of Missense Variations in the BRCT Domain of BRCA1 by Structural and Functional Assays. Lee MS, Green R, Marsillac ...
Saturday, May 29, 2010

Effect of BRCA2 sequence variants predicted to disrupt exonic splice enhancers on BRCA2 transcripts

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BACKGROUND: Genetic screening of breast cancer patients and their families have identified a number of variants of unknown clinical s...
Friday, May 14, 2010

Teal Toes: Women’s Health Week, Ovarian Cancer media/video - link between breast/ovarian cancers

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Note: no mention of other genetic risks aside from the BRCA's
Wednesday, April 21, 2010

Gene link to cancer risk in families - protein RAD51C (news item) breast and ovarian

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Note: this report is worthwhile reading especially for those who test negative for BRCA 1/2 "No significant mutations were found in ...
2 comments:
Sunday, March 28, 2010

Sleep disturbances in asymptomatic BRCA1/2 mutation carriers: women at high risk for breast-ovarian cancer

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"Fatigue and carrier status were significant predictors of sleep quality, accounting for 15.7% of the variance. In conclusion, asymptom...
Sunday, January 31, 2010

media article: The inherited malignancy of breast cancer (and ovarian cancer)

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Note: good article, albeit complicated subject matter - excerpts of important information:
Friday, January 29, 2010

Genetic Alliance Weighs in On AMP's Desire to Outlaw Gene Patenting GenomeWeb

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Wednesday, January 13, 2010

Molecular Cancer | Full text | Methylation and protein expression of DNA repair genes: association with chemotherapy exposure and survival in sporadic ovarian and peritoneal carcinomas

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full free access: Is no news good news? Inconclusive genetic test results in BRCA1 and BRCA2 from patients and professionals' perspectives

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Small study but included view of patients and physician views.