Friday, December 04, 2009
Tumor type and substage predict survival in stage I and II ovarian carcinoma: Insights and implications
Note: there is supplemental data that can be downloaded (word document) which is attached to this abstract - see link to view
Conclusions
A subset of ovarian carcinoma patients with an excellent outcome can be identified based on tumor type (endometrioid or mucinous) and stage (Ia or Ib). Type is more reproducibly assigned than grade and identifies a larger cohort of women with stage I/II ovarian carcinoma with favorable outcomes (12.2% vs. 6.5%), and therefore is superior to grade in estimating risk of death from ovarian carcinoma.
Gynecologic Oncology : Sequential chemotherapy with carboplatin followed by weekly paclitaxel in advanced ovarian cancer: Results of a multicenter phase II study of the northeastern German society of gynecological oncology
Gynecologic Oncology : Sequential chemotherapy with carboplatin followed by weekly paclitaxel in advanced ovarian cancer: Results of a multicenter phase II study of the northeastern German society of gynecological oncology
AHRQ Patient Safety Network - Patient Safety Primers
AHRQ Patient Safety Network - Patient Safety Primers: "The culture of individual blame still dominant and traditional in health care undoubtedly impairs the advancement of a safety culture. One issue is that, while 'no blame' is the appropriate stance for many errors, certain errors do seem blameworthy and demand accountability. In an effort to reconcile the twin needs for no-blame and appropriate accountability, the concept of 'just culture' is being introduced."
Thursday, December 03, 2009
Senate Affirms Screening Mammography for 40-Year-Olds - in Washington
In a 61 to 39 vote, the Senate dealt a significant blow to the power and credibility of the U.S. Preventive Services Task Force (USPSTF), by essentially deciding to disregard the task force's recent recommendation that women under 50 shouldn't undergo routine mammograms....
Drug company contributes $9 million to B.C.'s fight against cancer
Research in ovarian cancer will focus on identifying new biomarkers for diagnostic purposes as well as therapeutic targets
Recreational physical activity and risk of epithelial ovarian cancer
CONCLUSIONS: Our findings are compatible with an overall reduction in risk of invasive epithelial ovarian cancer associated with recreational activity but suggest that this association may differ in women with different histologic types of disease. Inconsistent findings across studies that have considered histologic type indicate that this issue is not yet resolved.
Wednesday, December 02, 2009
James Kreppner’s Obituary by the Toronto Star.
James Kreppner Death Notice
"KREPPNER, James Rudolf - March 6, 1962 to May 14, 2009 The world has lost an extraordinary human being. It is with profound sadness that the family announces the passing of James, a man possessed of a brilliant mind, gentle soul and tender heart, after a long, courageous and feisty battle with illness, on May 14, 2009, in his 47th year due to HIV and Hepatitis C-related complications...James was a highly respected, articulate and exemplary activist who represented the true meaning of fairness and kindness."
response to prior letter: HINI and Cancer
Note/background: Please reference prior blog postings Nov 1-5th, 2009 regarding the apparent lack of access to care of an ovarian cancer woman and the systemic issues surrounding the H1N1.
email response (better late than never) December 2, 2009 4:57 pm:
"Thank you for writing and bringing to my attention your concerns regarding the government’s handling of the H1N1 vaccine roll out. As you are aware, the vaccine is now available to all members of the public.
Your views and comments are appreciated and helpful to my work as Leader of Canada’s New Democrats.
Between the conflicting messages, queue jumping, and sole sourced contracts; we feel the federal government could have done a better job handling the distribution of the vaccine. NDP Health Critic Judy Wasylycia-Leis continues to be our lead on this issue and you can review her work by visiting: http://www.judywl.ndp.ca/news/health.
Looking forward, we will continue to press the federal government to take a proper role in helping Canadians stay healthy and providing access to treatment when needed through:
- promoting healthy living
- hiring and training more doctors and nurses
- creating a pan-Canadian home care program
- ensuring prescription medicines are affordable
If you are interested in our plans to improve health care in Canada, I encourage you to check for details here: http://www.ndp.ca/platform/healthcare.
Again, thank you for sharing your views and comments as they helpful to my work as Leader of Canada’s New Democrats. All the best.
Sincerely,
Jack Layton, MP (Toronto-Danforth)
Leader, Canada's New Democrats"
14-3-3σ, the double-edged sword of human cancers
highly technical paper, but the issues that always seem to find ovarian cancer at 'odds' with other cancers:
Despite the above findings that 14-3-3σ expression correlates with and may predict poor prognosis of breast, colorectal, prostate, and pancreatic cancers, opposite observations have also been made in other cancers including endometrium [61] and ovary [30], where it was found that the absence or low expression level of 14-3-3σ predicted poor survival or showed no correlation (see Table 1). In another study of 192 cases of ovarian cancer patients, no significant correlation between 14-3-3σ expression and survival was found [62]. Thus, it is possible that 14-3-3σ in prognosis prediction is cancer type dependent, and more detailed studies on this issue will be needed.
Subscribe to:
Posts
(
Atom
)
