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Wednesday, May 06, 2009

Cochrane Collaboration review/commentaries: Interventions for psychosexual dysfunction in women treated for gyn malignancy



Comments from Clinical Raters
Gynecology
A very useful review that confirms the need for proper randomised studies to answer this important question. My misgivings on the apparent lumping of all gynaecological malignancies together is that it creates an obviously flawed impression that sexual problems after treatment of gynaecological cancer of any kind might have a common solution.
Oncology - General
I was surprised to find that there was any evidence at all from randomised studies that addressed questions in this important area. The authors rightly draw attention to the paucity of evidence and its poor quality. As interest increases in what is now called cancer survivorship, we can anticipate an increasing need for solid evidence on which to base management for the complex difficulties experienced by patients successfully treated for cancer. This paper indicates that it is not going to be easy to assemble the necessary evidence.

Screening Tests Missing Early Signs of Ovarian Cancer - Oncology Nursing News



Screening Tests Missing Early Signs of Ovarian Cancer - Oncology Nursing News

Comment:
S. Pniauskas

Please also, and importantly, reference the recently published early detection ovarian cancer clinical trial by Dr Jacobs from the U.K.. Further, Dr Jacobs completed a study of 22,000 women over a decade ago with the same results. So, nothing has changed even after all of this time which is very sad. So much time has elapsed, so many deaths and sufferings. A coordinated international effort is needed badly and while new research is hopeful, our ovarian cancer communities have faced extreme dissapointments with even new and 'apparent' early detection tests of recent years. It would be seriously disconcerting to know that another decade may lapse without any definitive results. This does not take away from the goodwill and integrity of the research/ers, but a more effective and coordinated effort is needed.

Researchers Detail Chemotherapy's Damage to the Brain - URMC Press Room




NCI: Delving Into Possible Mechanisms for Chemobrain



NCI Cancer Bulletin for March 24, 2009 - National Cancer Institute

Time-related communication skills from the cancer patient perspective




Analysis of gene expression in stage I serous tumors identifies critical pathways altered in ovarian cancer




Mortality rates due to gynecologic cancers in New York state by demographic factors and proximity to a GOG group member treatment center: 1979-2001



High Incidence of Hypocalcemia and Serum Creatinine Increase in Patients with Bone Metastases Treated with Zoledronic Acid




Improved progression free and overall survival in advanced cancer as a result of a change in sugical paradigm



"PFS rates were 31% vs 14%"

Are surveillance procedures of clinical benefit for patients treated for ovarian cancer?



Practice patterns of intraperitoneal chemotherapy in women with ovarian cancer.



"Practice patterns of intraperitoneal chemotherapy in women with ovarian cancer."