full free access: PLoS ONE: Genetic Analysis of the Early Natural History of Epithelial Ovarian Carcinoma Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Monday, April 26, 2010

full free access: PLoS ONE: Genetic Analysis of the Early Natural History of Epithelial Ovarian Carcinoma



Conclusions/Significance

Together, these data indicate that EOC frequently arises in ovarian cystic inclusions, is preceded by an identifiable dysplastic precursor lesion, and that increased cell proliferation, decreased apoptosis, and aneuploidy are likely to represent very early aberrations in ovarian tumorigenesis.

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