OVARIAN CANCER and US: genetic analysis

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Showing posts with label genetic analysis. Show all posts
Showing posts with label genetic analysis. Show all posts

Monday, April 26, 2010

full free access: PLoS ONE: Genetic Analysis of the Early Natural History of Epithelial Ovarian Carcinoma



Conclusions/Significance

Together, these data indicate that EOC frequently arises in ovarian cystic inclusions, is preceded by an identifiable dysplastic precursor lesion, and that increased cell proliferation, decreased apoptosis, and aneuploidy are likely to represent very early aberrations in ovarian tumorigenesis.