Molecular typing of epithelial ovarian carcinomas using inflammatory markers - Ali-Fehmi - 2010 - Cancer - Wiley Online Library Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Monday, September 06, 2010

Molecular typing of epithelial ovarian carcinomas using inflammatory markers - Ali-Fehmi - 2010 - Cancer - Wiley Online Library



Abstract
BACKGROUND:


Ovarian epithelial carcinomas have recently been classified as slow growing type I tumors and rapidly growing highly aggressive type II tumors. The present study sought to molecularly characterize type I and II tumors using known molecular markers.

CONCLUSIONS:

The present study demonstrates that the new proposed histologic classification of ovarian epithelial carcinomas correlates with a distinct expression of inflammatory pathway proteins. High expression of these markers may explain the different biologic behavior of these 2 tumor types and provide targets for therapy.

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