OVARIAN CANCER and US: molecular characteristic

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Showing posts with label molecular characteristic. Show all posts
Showing posts with label molecular characteristic. Show all posts

Monday, September 06, 2010

Molecular typing of epithelial ovarian carcinomas using inflammatory markers - Ali-Fehmi - 2010 - Cancer - Wiley Online Library



Abstract
BACKGROUND:


Ovarian epithelial carcinomas have recently been classified as slow growing type I tumors and rapidly growing highly aggressive type II tumors. The present study sought to molecularly characterize type I and II tumors using known molecular markers.

CONCLUSIONS:

The present study demonstrates that the new proposed histologic classification of ovarian epithelial carcinomas correlates with a distinct expression of inflammatory pathway proteins. High expression of these markers may explain the different biologic behavior of these 2 tumor types and provide targets for therapy.