Endometriosis and ovarian cancer – Authors' reply : The Lancet Oncology

Endometriosis and ovarian cancer – Authors' reply : The Lancet Oncology

"Both Vercellini and colleagues and Guo and colleagues raise concerns about screening, with which we agree. Our findings should not suggest to clinicians or the public that screening for ovarian cancer should be implemented for women with endometriosis. Rather, we hope that our work stimulates further research that can refine risk groups related to endometriosis on the basis of anatomical site, epidemiological risk factors, or molecular features. Vercellini and colleagues raise an interesting point about atypical endometriosis, but this diagnosis is not standardised or commonly used and can not be addressed in epidemiological studies.

..................Regardless, the attenuated associations remain statistically significant.