Endometriosis and ovarian cancer – Authors' reply : The Lancet Oncology
"Both Vercellini and colleagues and Guo and
colleagues raise concerns about screening, with which we agree. Our
findings should not suggest to clinicians or the public that screening
for ovarian cancer should be implemented for women with endometriosis.
Rather, we hope that our work stimulates further research that can
refine risk groups related to endometriosis on the basis of anatomical
site, epidemiological risk factors, or molecular features. Vercellini
and colleagues raise an interesting point about atypical endometriosis,
but this diagnosis is not standardised or commonly used and can not be
addressed in epidemiological studies.
..................Regardless, the attenuated associations remain statistically
significant.
