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Abstract Results and Conclusions:
Results
We did not find evidence of an association between consumption of sugary foods and
beverages and risk, although there was a suggestion of increased risk associated with
sugary drink intake (servings per 1,000 kcal; OR=1.63, 95% CI: 0.94-2.83).
Conclusions
Overall, we found little indication that sugar intake played a major role on ovarian
cancer development.
Conclusions
To our knowledge this is the first study to evaluate ovarian cancer risk in relation to total and individual consumption of sugary foods and beverages, total and added sugar intake, as well as a potential effect modification by several insulin-related risk factors. Although in our study there was a suggestion of a moderately increased cancer risk associated with sugary beverage consumption, overall, we did not detect significant relationships with any of the sugar variables evaluated. The overall evidence for sugary foods and drinks and added sugars remains inconclusive. These apparent gaps in the literature emphasize the need for future research, preferably large prospective studies, to evaluate the role of added sugars in the etiology of ovarian cancer, while taking into consideration various factors capable of influencing the body’s insulin response such as anthropometric measures and physical activity.
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