Familial and Atypical Urothelial Cancer Registry (still recruiting)

ClinicalTrials.gov

Purpose

This study is being done to create a registry to help us learn more about urinary and other cancers. This will let us look at large groups of people who do and do not have this kind of cancer.

The investigators will look at risk factors to learn more about how these impact cancer. The investigators will also look at genetic markers. These are genes that are found in a known place. They are often associated with a particular trait. If the gene changes in some way, it may predict cancer or response to treatment. The investigators will look for markers in your saliva.

This registry will help us develop better methods of:

Preventing these cancers. Diagnosing these cancers. Treating these cancers.

Condition	Intervention
Urothelial Cancer Renal Pelvis Cancer Ureter Cancer Bladder Cancer	Other: saliva sample and questionaire Other: saliva sample, questionaire

Study Type:	Observational
Study Design:	Observational Model: Case Control Time Perspective: Prospective
Official Title:	Familial and Atypical Urothelial Cancer Registry		Eligibility Ages Eligible for Study:   18 Years and older Genders Eligible for Study:   Both Accepts Healthy Volunteers:   Yes Sampling Method:   Non-Probability Sample Study Population A member of the patient's treatment team, the protocol investigator, or a member of the research team at Memorial Sloan-Kettering Cancer Center (MSKCC) will identify potential research subjects. At MSKCC the following outpatient clinics will be used to recruit UC cases: Urology and Genitourinary Oncology. Patients and families may also be directly referred to the study team by any MSKCC physician, external physician, or by the family itself. Criteria Inclusion Criteria: Urothelial Cancer Cases Must be ≥ 18 years of age AND Must have a diagnosis of urothelial cancer AND Must be an English-speaker