Incidence, Trends and Morphology of Ovarian Cancer in Karachi (1995-2002)

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Conclusions: The incidence of cancer ovary, though stable in Karachi (South Pakistan), involves a relatively younger age group (see Table 1) with a strong family history in a fourth of the cases. The disease presents at an advanced stage. An ageing population over time may translate into a higher incidence of ovarian cancer. The current incidence of cancer ovary in Karachi is an enigma and belies reproductive protective factors. Studies focused on the genetic risk factors in this population are recommended.