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Abstract
"Lynch syndrome is a genetic disease, caused by a
germ-line mutation in a mismatch repair gene, related to an increased
risk of developing colorectal and extracolonic cancer. Despite that, the
incidence of primary peritoneal cancer after adnexectomy remains
unknown. We here report a case of primary peritoneal cancer in a woman
affected by Lynch syndrome who underwent
hysterectomy+salpingo-oophorectomy for endometrial cancer 13 yr before.
Morphology and immunophenotype allowed to differentiate peritoneal
malignancy from the previously diagnosed endometrial carcinoma.
Physicians should be aware of the potential risk of primary peritoneal
cancer in women affected by Lynch syndrome, despite previous
prophylactic surgery.
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