New Endpoints Proposed for Chemotherapy in Ovarian Cancer Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Tuesday, June 18, 2013

New Endpoints Proposed for Chemotherapy in Ovarian Cancer



Medscape

" Quality of life (QoL) and symptom benefit should be accepted by clinicians and regulators as additional coprimary endpoints in clinical trials of chemotherapies for platinum-resistant and refractory ovarian cancer, according to a group of experts....

refers to prior post/publication:

Clinical Trials of Palliative
Chemotherapy in Platinum-Resistantor -Refractory Ovarian Cancer: Timeto Think Differently?

1 comment :

  1. Those Who Can, Do - Those Who Can't, Change The Rules!

    "These measures are "the most important aims of treatment" in these patients because improvements in overall and progression-free survival (OS and PFS) have hit a ceiling in trial after trial of chemotherapies,"

    Priceless Quote!

    I personally think this is scandalous. What they are saying is that they are not coming up with any drugs which are any better than the drugs that they have been using all along. So big Pharma has no new drugs to sell. So they change the goal line. Or, more accurately, they lower the bar. Progression free survival and overall survival are hard objective endpoints. Quality of life is totally squishy and unobjective. So future clinical trials in cancer are going to be designed and scored by psychologists. Patients should never ever let them get away with this. Their feet should be held close to the fire. Shame on them.

    ReplyDelete

Your comments?

Note: Only a member of this blog may post a comment.

1 comment :

  1. Those Who Can, Do - Those Who Can't, Change The Rules!

    "These measures are "the most important aims of treatment" in these patients because improvements in overall and progression-free survival (OS and PFS) have hit a ceiling in trial after trial of chemotherapies,"

    Priceless Quote!

    I personally think this is scandalous. What they are saying is that they are not coming up with any drugs which are any better than the drugs that they have been using all along. So big Pharma has no new drugs to sell. So they change the goal line. Or, more accurately, they lower the bar. Progression free survival and overall survival are hard objective endpoints. Quality of life is totally squishy and unobjective. So future clinical trials in cancer are going to be designed and scored by psychologists. Patients should never ever let them get away with this. Their feet should be held close to the fire. Shame on them.

    ReplyDelete

Your comments?

Note: Only a member of this blog may post a comment.