Venous Thromboembolism Risk in Patients With Cancer Receiving Chemotherapy: A Real-World Analysis

abstract

Types of tumor associated with the highest VTE risk are hematologic  cancers,followed by lung,pancreatic,stomach,ovarian,uterine,bladder,and brain

 tumors.

Implications for Practice:

This large observational study of unselected patients receiving cancer 

chemotherapy demonstrates considerably greater rates of venous 

thromboembolism (VTE) than commonly reported in patients accrued to clinical trials.The risk of VTE appears to increase progressively over the year following initiation of treatment. Cancer patients

developing VTE also experience a greater risk of major bleeding and greater health care costs than patients without VTE.

Patients considered at high risk for VTE should be considered for 

thromboprophylaxis after assessing the balance of potential benefits and harms.