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Ovarian Cancers: Evolving Paradigms in Research and Care
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The Biology of Ovarian Cancer
Recent evidence suggests that many ovarian carcinomas do not arise in
the ovary. Furthermore, researchers do not have a complete understanding
for each subtype of how the disease progresses or the effects of the microenvironment.
Without better model systems that replicate the manifestations
of the human disease, the answers to many key questions will remain
elusive. This research gap is further complicated by the significant degree
of heterogeneity of ovarian carcinomas, including within and between subtypes.
However, clinicians and researchers tend to combine them in many
types of research......
The Biology of Ovarian Cancer
Recent evidence suggests that many ovarian carcinomas do not arise in
the ovary. Furthermore, researchers do not have a complete understanding
for each subtype of how the disease progresses or the effects of the microenvironment.
Without better model systems that replicate the manifestations
of the human disease, the answers to many key questions will remain
elusive. This research gap is further complicated by the significant degree
of heterogeneity of ovarian carcinomas, including within and between subtypes.
However, clinicians and researchers tend to combine them in many
types of research......
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