abstract
BACKGROUND:
Use
of risk assessment tools, such as the Caprini score or Rogers score, is
recommended by national societies to stratify surgical patients by
venous thromboembolism (VTE) risk and guide prophylaxis. However, these
tools were not developed in a gynecologic oncology patient population
and their utility in this population is unknown.
OBJECTIVE:
To examine the ability of both the Caprini and Rogers score to stratify gynecologic oncology patients by risk of VTE.
CONCLUSIONS:
Gynecologic
oncology patients score very high on current VTE risk assessment
models. The Caprini score is limited in its ability to discriminate
relative VTE risk among gynecologic oncology patients as 97% are in the
highest-risk category. Sub-stratification of the highest risk groups
allows for relative VTE risk stratification among gynecologic oncology
patients suggesting that further evaluation of risk stratification is
needed in gynecologic oncology surgery.
STUDY DESIGN:
Patients undergoing surgery for cervical,
ovarian,
uterine, vaginal and vulvar cancers between 2008 and 2013 were
identified from the National Surgical Quality Improvement Database using
ICD-9 codes. Caprini and Rogers scores were calculated for each patient
based upon recorded demographic and procedure data. VTE events were
recorded for 30 days postoperatively. Patients were categorized into
risk groups based on calculated Caprini and Rogers scores and the
incidence of VTE and 95% confidence interval was estimated for each of
these groups. The relationship between risk score and VTE incidence was
examined with Pearson's correlation coefficient.
RESULTS:
Of
17,713 patients, 1.8% developed a VTE. No patients were classified by
the Caprini score as low risk, 0.1% were moderate risk, 3.0% were higher
risk (score 4), and 96.9% were highest risk (score >=5). The Caprini
score groupings did not correlate with VTE. The high-risk group had a
paradoxically higher incidence of VTE of 2.5% compared to the highest
risk group, 1.7% (p=0.40). However, when the highest risk group of the
Caprini score was sub-stratified, it was highly correlated with VTE (R
2=0.93).
For the Rogers score, only 0.2% of patients were low risk (score
<7), 36.9% were medium risk (score 7-10), and 63.0% were high-risk
(score >10). When the highest risk group of the Rogers score was
sub-stratified, it was also highly correlated with VTE (R
2=0.99).
CONCLUSIONS:
Gynecologic
oncology patients score very high on current VTE risk assessment
models. The Caprini score is limited in its ability to discriminate
relative VTE risk among gynecologic oncology patients as 97% are in the
highest-risk category. Sub-stratification of the highest risk groups
allows for relative VTE risk stratification among gynecologic oncology
patients suggesting that further evaluation of risk stratification is
needed in gynecologic oncology surgery.
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