DNA Analysis in Samples From Younger Patients With Germ Cell Tumors and Their Parents or Siblings

ClinicalTrials.gov

 Purpose

This research trial studies deoxyribonucleic acid (DNA) samples from younger patients with germ cell tumor and their parents or siblings. Studying samples of tumor tissue and saliva from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.

Condition	Intervention
Childhood Malignant Ovarian Germ Cell Tumor Childhood Malignant Testicular Germ Cell Tumor Ovarian Choriocarcinoma Ovarian Embryonal Carcinoma Ovarian Mixed Germ Cell Tumor Ovarian Teratoma Ovarian Yolk Sac Tumor Testicular Choriocarcinoma Testicular Embryonal Carcinoma Testicular Seminoma Testicular Teratoma Testicular Yolk Sac Tumor	Other: laboratory biomarker analysis Other: questionnaire administration

Study Type:	Observational
Study Design:	Observational Model: Family-Based Time Perspective: Prospective
Official Title:	Molecular Epidemiology of Pediatric Germ Cell Tumors