Comment: A prognostically relevant miRNA signature for epithelial ovarian cancer

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A prognostically relevant miRNA signature for epithelial ovarian cancer

• Summary

Although only about 30% of women who present with distant metastatic ovarian cancer will survive for 5 years or more, this proportion is considerably better than that for those individuals who present with advanced cervical, colorectal, kidney, or pancreatic cancer.¹ This provides rationale for the relevance of identifying prognostic biomarkers for ovarian cancer to predict outcome and improve understanding of the biological basis of chemotherapy resistance and disease progression. A prognostic gene expression signature has been described for high-grade serous carcinoma, the most common form of epithelial ovarian cancer.

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