Comment: A prognostically relevant miRNA signature for epithelial ovarian cancer Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Wednesday, July 13, 2016

Comment: A prognostically relevant miRNA signature for epithelial ovarian cancer



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Although only about 30% of women who present with distant metastatic ovarian cancer will survive for 5 years or more, this proportion is considerably better than that for those individuals who present with advanced cervical, colorectal, kidney, or pancreatic cancer.1 This provides rationale for the relevance of identifying prognostic biomarkers for ovarian cancer to predict outcome and improve understanding of the biological basis of chemotherapy resistance and disease progression. A prognostic gene expression signature has been described for high-grade serous carcinoma, the most common form of epithelial ovarian cancer.

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