Medical News: BRCA Mutations Also Play Good Role in Ovarian Cancer - in Oncology/Hematology, Ovarian Cancer from MedPage Today

Action Points

---

• A pooled analysis of 26 observational studies found that five-year survival was significantly improved for invasive epithelial ovarian cancer patients carrying BRCA1 or BRCA2 mutations compared with noncarriers.



• Note that data on treatment differences among the heterogeneous population were not available, there were missing data, and procedures for screening for the mutations differed among the studies.

Targeted Cryoablation Boosts Survival in Ovarian Cancer

"......"This treatment is strictly to alleviate symptoms attributed to disease progression in a cost-effective manner," Dr. Bang explained. "Survival benefit is merely a direct effect in the efficacy of cryoablation, which was able to successfully ablate tumors in 98% of cases."..........

A systematic review evaluating the relationship between Progression free survival and Post Progression survival in advanced ovarian cancer

Nomogram for predicting 5-year disease-specific mortality after primary surgery for epithelial ovarian cancer

Clinical Oncology News - Earlier Dx of Ovarian Ca Not Associated With Improved Survival + Commentary (Markman)