Showing posts with label 6-thioguanine. Show all posts
Showing posts with label 6-thioguanine. Show all posts
Friday, July 16, 2010
6-Thioguanine Selectively Kills BRCA2-Defective Tumors and Overcomes PARP Inhibitor Resistance
"Altogether, our data show that 6TG efficiently kills BRCA2-defective tumors and suggest that 6TG may be effective in the treatment of advanced tumors that have developed resistance to PARP inhibitors or platinum-based chemotherapy. Cancer Res; 70(15); OF1-9. (c)2010 AACR."
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