OVARIAN CANCER and US: Maspin

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Showing posts with label Maspin. Show all posts
Showing posts with label Maspin. Show all posts

Friday, January 22, 2010

BRCA1 185delAG mutant protein, BRAt, up-regulates Maspin in ovarian epithelial cells



"Consequently, understanding early genotypic and phenotypic changes in the context of high risk disease may provide a better understanding of the mechanism of mutation-associated ovarian cancer and provide new targets for therapeutic intervention."