OVARIAN CANCER and US: Ovarian cancer; Endometriosis; Pathogenesis; Oxidative stress; Microarray; Clear cell carcinoma; Microenvironment

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Showing posts with label Ovarian cancer; Endometriosis; Pathogenesis; Oxidative stress; Microarray; Clear cell carcinoma; Microenvironment. Show all posts
Showing posts with label Ovarian cancer; Endometriosis; Pathogenesis; Oxidative stress; Microarray; Clear cell carcinoma; Microenvironment. Show all posts

Monday, July 11, 2011

abstract - Cancer Letters : Ovarian Clear Cell Carcinoma as a Stress-Responsive Cancer: Influence of the Microenvironment on the Carcinogenesis and Cancer Phenotype



 Highlights


► Ovarian endometriosis is known to transform into ovarian cancer, but its etiology is not clarified.
► A stressful microenvironment within the endometriotic cyst may lead to cancer development.
► Ovarian clear cell carcinoma has unique gene expressions, which may serve as a molecular marker.
► Carcinogenic microenvironment affects the phenotype, character and gene expression of a cancer.
► We might be able to develop new treatment based on the analysis of the influence of microenvironment.