OVARIAN CANCER and US: Pfizer

Blog Archives: Nov 2004 - present

#ovariancancers



Special items: Ovarian Cancer and Us blog best viewed in Firefox

Search This Blog

Showing posts with label Pfizer. Show all posts
Showing posts with label Pfizer. Show all posts

Sunday, May 29, 2011

Expert Opinion on Investigational Drugs -Investigational antibody drug conjugates for solid tumors Summary (Pfizer)



Note: access to the full article is payer-per-view ($$$)

"Despite the progress made in the past 20 years in understanding the molecular events leading to the formation of cancer, the success of targeted antitumor agents in solid tumors has lagged behind the scientific discoveries. The most difficult to treat patient segments are those with refractory solid tumors, resistant to standard chemotherapy, and novel therapeutic compounds with improved therapeutic indexes are needed. Antibody drug conjugates (ADCs) are poised to become an important class of cancer therapeutics, as evidenced by the promising objective response rates when administered as single agents to chemorefractory cancer patients..........Herein, we review ADCs (Antibody drug conjugates) targeting solid tumors, with the focus on 11 programs currently undergoing clinical development....)