Roche's Avastin - Trials And Triumphs (overview/history)

message from Colorectal Cancer Assoc of Canada - Roche study requests colorectal cancer participants - Montreal, Toronto, Vancouver

Note: message received Jan 17th, deadline Jan 13th ??

financial news: PREVIEW-New cancer data may be tonic for sickly Roche | Reuters

"Frings said Roche would file for European regulatory approval of Avastin in ovarian cancer by the end of the year, with a U.S. submission following in 2011."

Curis announces preliminary results of GDC-0449 Phase II clinical trial in advanced ovarian cancer - press release

".... Accordingly, Roche and Genentech have indicated that they plan to further analyze the data, including subset analyses in the coming months. Following these analyses, they expect to make a portfolio decision regarding whether, or to what extent, they will continue development of GDC-0449 in advanced ovarian cancer.

“While we await the final analysis of the data from this advanced ovarian cancer study, we remain optimistic about the continued evaluation of GDC-0449 in tumors such as basal cell carcinoma”

No obvious new safety signals were observed in patients treated with GDC-0449. It is expected that data from this Phase II study will be submitted for presentation at an upcoming medical meeting....cont'd

PharmaLive: Curis / GDC-0449 [phase 11 trial results to follow

Note:  excerpt - Avastin + chemo

"Genentech and Roche are also conducting a randomized double-blind placebo-controlled Phase II trial in advanced ovarian cancer in a maintenance setting, which is evaluating the ability of GDC-0449 to slow the time to recurrence of cancer in patients whose disease is in complete remission, by impeding the residual cancer cells' ability to grow. Roche has indicated that results from this study are expected during the second half of 2010."