Blogger's Note: see also posting regarding BRCA1/heart disease/doxorubicin research... (blog posting Apr 3 eg. as per below abnormal lipid levels/ovarian cancer)
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Cancer among patients with diabetes, obesity and abnormal blood lipids: a population-based register study in Sweden.
Abstract
OBJECTIVE:
To study how the incidence of cancer is related to diabetes, obesity or abnormal blood lipids.
METHODS:
Diagnosis
of diabetes, obesity or abnormal blood lipids was studied 0-10 years
prior to the diagnosis of cancer in 19,756 cases of cancer and in
147,324 controls matched regarding age, sex and domicile.
RESULTS:
Diabetes
was significantly more common prior to diagnosis in patients with
liver, pancreatic, colon and urinary tract/bladder cancer and in
patients with breast cancer diagnosed with diabetes 0-4 years prior to
the cancer diagnosis. A lower risk of diabetes was seen in patients with
prostate carcinoma among individuals with diabetes diagnosed 5-10 years
prior to the cancer diagnosis. The findings remained after adjusting
for obesity and high blood lipids. Obesity was significantly more common
in patients with endometrial, colon and kidney cancer and with breast
cancer above the age of 60 years in those where obesity was diagnosed
close to the diagnosis of cancer. High blood lipids were significantly
more common in patients with ovarian cancer and less common in patients
with breast cancer.
CONCLUSIONS:
The study confirms some previous findings concerning comorbidity and cancer and highlights some new ones.
