Showing posts with label antibiotics. Show all posts
Showing posts with label antibiotics. Show all posts
Wednesday, February 08, 2012
Evidence Updates: Antibiotic prophylaxis for bacterial infections in afebrile neutropenic patients following chemotherapy. Cochrane Database Syst Rev includes professional commentaries
AUTHORS' CONCLUSIONS:
Antibiotic prophylaxis in afebrile neutropenic patients significantly reduced all-cause mortality.
In our review, the most significant reduction in mortality was observed in trials assessing prophylaxis with quinolones. The benefits of antibiotic prophylaxis outweighed the harm such as adverse effects and the development of resistance since all-cause mortality was reduced. As most trials in our review were of patients with haematologic cancer, we strongly recommend antibiotic prophylaxis for these patients, preferably with a quinolone.
Prophylaxis may also be considered for patients with solid tumours or lymphoma.
Alternate source/link
Wednesday, July 13, 2011
abstract: Antibiotic use and risk of gynecological cancers (Saskatchewan database)
OBJECTIVES: Several studies addressed the association between antibiotic use and breast cancer risk. The objective of this study was to assess the association between antibiotic use and risk of cervical, ovarian, and uterine cancer.
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