OVARIAN CANCER and US: colon cancer

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Showing posts with label colon cancer. Show all posts
Showing posts with label colon cancer. Show all posts

Wednesday, February 01, 2012

abstract: Clinical Effects of Adjuvant Active Specific Immunotherapy Differ between Patients with Microsatellite-Stable and Microsatellite-Instable Colon Cancer



Blogger's Note:  the abstract does not detail MSI-L/MSI-H (colon cancer in Lynch Syndrome)


Experimental Design:
Microsatellite status was assessed on archival tumor material from patients with stage II and III colon cancer. Microsatellite status was next associated with clinical outcome in control and ASI treatment groups using Kaplan–Meier analysis.



Conclusion:

This retrospective study indicated that patients with MSI tumors did well, irrespective of treatment arm and tumor stage. The data also indicate that the clinical benefit, measured as recurrence-free survival, from adjuvant ASI treatment of patients with colon cancer was restricted to patients with MSS Dukes B tumors

Wednesday, February 10, 2010