Traitorous Immune Cells Promote Sudden Ovarian Cancer Progression | Wistar

Wiki:  
Dendritic cells (DCs) are immune cells forming part of the mammalian immune system. Their main function is to process antigen material and present it on the surface to other cells of the immune system. That is, dendritic cells function as antigen-presenting cells. They act as messengers between the innate and adaptive immunity.

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"Aggressive ovarian tumors begin as malignant cells kept in check by the immune system until, suddenly and unpredictably, they explode into metastatic cancer. New findings from José R. Conejo-Garcia's lab demonstrate that ovarian tumors don’t necessarily break “free” of the immune system, rather dendritic cells of the immune system seem to actively support the tumor’s escape. The researchers show that it might be possible to restore the immune system by targeting a patient’s own dendritic cells....."