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Showing posts with label female. Show all posts
Showing posts with label female. Show all posts

Wednesday, August 10, 2011

EvidenceUpdates - Strategies to identify the lynch syndrome among patients with colorectal cancer: a cost-effectiveness analysis. (focus on women/risk reduction strategies) - abstract



"..... At current rates of germline testing, screening, and prophylactic surgery, the strategies reduced deaths from colorectal cancer by 7% to 42% and deaths from endometrial and ovarian cancer by 1% to 6%....."  

CONCLUSION: Widespread colorectal tumor testing to identify families with the Lynch syndrome could yield substantial benefits at acceptable costs, particularly for women with a mutation associated with the Lynch syndrome who begin regular screening and have risk-reducing surgery. The cost-effectiveness of such testing depends on the participation rate among relatives at risk for the Lynch syndrome.

Ratings (on article/professionals) pending – login (free) to http://plus.mcmaster.ca/evidenceupdates in a few days if interested.