OVARIAN CANCER and US: histone deacetylase inhibitor

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Showing posts with label histone deacetylase inhibitor. Show all posts
Showing posts with label histone deacetylase inhibitor. Show all posts

Tuesday, March 23, 2010

Phase II trial of the histone deacetylase inhibitor belinostat in women with platinum resistant epithelial ovarian cancer and micropapillary (LMP) ovarian tumours



Phase II trial of the histone deacetylase inhibitor belinostat in women with platinum resistant epithelial ovarian cancer and micropapillary (LMP) ovarian tumours.

CONCLUSIONS: Belinostat is well tolerated in both patient groups and shows some activity in patients with micropapillary (LMP) disease.