Complete clinical responses to cancer therapy caused by multiple diver
Complete clinical responses to cancer therapy caused by multiple divergent approaches: a repeating theme lost in translation (click on 'pdf' for full paper; references to ovarian cancer; hormonal therapy; angiogenesis...)
Abstract:
Over 50 years of cancer therapy history reveals complete clinical responses (CRs) from remarkably divergent forms of therapies (eg, chemotherapy, radiotherapy, surgery, vaccines, autologous cell transfers, cytokines, monoclonal antibodies) for advanced solid malignancies occur with an approximately similar frequency of 5%–10%. This has remained frustratingly almost static.
However, CRs usually underpin strong durable 5-year patient survival. How can this apparent paradox be explained?
