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Showing posts with label individualized treatment of patients with advanced stage ovarian cancer. Show all posts
Showing posts with label individualized treatment of patients with advanced stage ovarian cancer. Show all posts

Tuesday, February 21, 2012

Retraction: An Integrated Genomic-Based Approach to Individualized Treatment of Patients With Advanced-Stage Ovarian Cancer



Retraction

An Integrated Genomic-Based Approach to Individualized Treatment of Patients With Advanced-Stage Ovarian Cancer” by Holly K. Dressman, Andrew Berchuck, Gina Chan, Jun Zhai, Andrea Bild, Robyn Sayer, Janiel Cragun, Jennifer Clarke, Regina S. Whitaker, LiHua Li, Jonathan Gray, Jeffrey Marks, Geoffrey S. Ginsburg, Anil Potti, Mike West, Joseph R. Nevins, and Johnathan M. Lancaster (J Clin Oncol 25:517–525, 2007)
The majority of the authors wish to retract this article because they have identified several instances of misalignment of genomic and clinical outcome data. Although a reanalysis of correctly aligned data still demonstrated a capacity to predict patient response to platinum-based therapy, the accuracy of these predictions has been reduced from 77.8% to 72.2%, and as a result, the original conclusions have been compromised. The authors deeply regret the impact of this action on the work of other investigators.
The following authors agreed with this retraction decision: Andrew Berchuck, Gina Chan, Janiel Cragun, Holly K. Dressman, Geoffrey S. Ginsburg, Jonathan Gray, Johnathan M. Lancaster, Jeffrey Marks, Joseph R. Nevins, Anil Potti, Mike West, and Regina S. Whitaker.
The following authors disagreed with this retraction decision: Andrea Bild, Jennifer Clarke, LiHua Li, and Jun Zhai.
The following author could not be reached for comment: Robyn Sayer.
This article was retracted on January 27, 2012.