full free access: More stakeholder engagement is needed to improve quality of research, say US experts

Blogger's note: Agree  based on years of RCT reviews

"Researchers need to overcome the evidence paradox of 18 000 randomised trials being published each year but almost every review concluding that not enough hard evidence exists to actually inform decision making, experts have said."

"We can’t just keep putting band aids on this system," she said. "Either health care is going to be subject to scientific methods and actually become evidence based or we are just going to keep generating little bits of evidence here and there and valiantly try to assemble them into some kind of path forward."

Intrauterine device use among women with ovarian cancer: a systematic review

Results

Of the 250 articles identified by our search strategy, none provided evidence (direct or indirect) regarding the safety of IUD use among women with ovarian cancer.

Conclusions

No evidence on the safety of IUD use among women with ovarian cancer was identified. While there are some theoretical concerns that IUD use might affect monitoring of disease progression of sex cord-stromal (non-epithelial ovarian) tumors, or increase risk of pelvic infection or vaginal bleeding among women undergoing chemotherapy, we did not find any data to suggest that IUD use would lead to worsening of primary ovarian cancer.