OVARIAN CANCER and US: latitude

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Showing posts with label latitude. Show all posts
Showing posts with label latitude. Show all posts

Tuesday, August 10, 2010

Casting light on 25-hydroxyvitamin D deficiency in ovarian cancer: A study from the NHANES (National Health and Nutrition Examination Surveys)



Abstract

Objectives

Ecological studies have long described a higher incidence of ovarian cancer in more extreme latitudes, where sun exposure, and presumably vitamin D exposure, is lower. Basic science studies have also noted polymorphisms of the vitamin D receptor in ovarian cancers. The aim of this study is to examine the relationship of serum vitamin D to ovarian cancer.

Conclusions

Prevalent ovarian cancer cases have lower serum 25-hydroxyvitamin D (25[OH]D) than the general population. Deficiency in vitamin D may provide an etiologic link between the long-known ecologic findings regarding latitude and the basic science noting polymorphisms in the vitamin D receptor.