OVARIAN CANCER and US: methylation

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Showing posts with label methylation. Show all posts
Showing posts with label methylation. Show all posts

Thursday, June 03, 2010

Stem cell researchers uncover previously unknown patterns in DNA methylation



"The findings could have implications in fighting cancer because DNA methylation patterns go awry in cancer, often causing tumor suppressor genes to switch off. The more scientists know about the cellular mechanisms that lay down the correct DNA methylation patterns, the more that process can be manipulated. In the future, this type of research may lead to techniques that result in the ability to control the patterns that go awry and lead to cancer, thus preventing a malignancy"

Thursday, February 25, 2010

full access: DNA Methylation Profiles of Ovarian Epithelial Carcinoma Tumors and Cell Lines



Table 1
Histology and clinical characteristics of primary ovarian tumors. (serous, endometrioid, clear cell - CA125 levels, menopausal status,patient age)
Background
Epithelial ovarian carcinoma is a significant cause of cancer mortality in women worldwide and in the United States. Epithelial ovarian cancer comprises several histological subtypes, each with distinct clinical and molecular characteristics. The natural history of this heterogeneous disease, including the cell types of origin, is poorly understood.