Conjugated equine oestrogen and breast cancer incidence and mortality in postmenopausal women with hysterectomy: extended follow-up of the Women's Health Initiative randomised placebo-controlled trial : The Lancet Oncology
Interpretation
Our
findings provide reassurance for women with hysterectomy seeking relief
of climacteric symptoms in terms of the effects of oestrogen use for
about 5 years on breast cancer incidence and mortality. However, our
data do not support use of oestrogen for breast cancer risk reduction
because any noted benefit probably does not apply to populations at
increased risk of such cancer.