Showing posts with label oophorectomy. Show all posts
Showing posts with label oophorectomy. Show all posts
Saturday, May 05, 2012
paywalled: Prophylactic oophorectomy rates in relation to a guideline update on referral to genetic counseling
Prophylactic oophorectomy rates in relation to a guideline update on referral to genetic counseling: Publication year: 2012
Source: Gynecologic Oncology
Objective We sought to determine whether prophylactic oophorectomy rates changed after the introduction of a 2007 health plan clinical guideline recommending systematic referral to a genetic counselor for women with a personal or family history suggestive of an inherited susceptibility to breast/ovarian cancer.
Methods We conducted a retrospective cohort study of female members of Group Health, an integrated delivery system in Washington State. Subjects were women aged ≥35years during 2004–2009 who reported a personal or family history consistent with an inherited susceptibility to breast/ovarian cancer. Personal and family history information was collected on a questionnaire completed when the women had a mammogram. We ascertained oophorectomies from automated claims data and determined whether surgeries were prophylactic by medical chart review.....
Results Prophylactic oophorectomy rates were relatively unchanged after compared to before the guideline change, 1.0 versus 0.8/1,000 person-years, (IRR=1.2; 95% CI: 0.7-2.0), whereas bilateral oophorectomy rates for other indications decreased. Genetic counseling receipt rates doubled after the guideline change (95% CI: 1.7-2.4) from 5.1 to 10.2/1,000 person-years. During the study, bilateral oophorectomy rates were appreciably greater in women who saw a genetic counselor compared to those who did not regardless of whether they received genetic testing as part of their counseling.
Conclusion A doubling in genetic counseling receipt rates lends support to the idea that the guideline issuance contributed to sustained rates of prophylactic oophorectomies in more recent years.
add your opinions
family history
,
genetic counseling
,
genetic testing
,
oophorectomy
,
ovarian cancer prevention
,
prophylactic surgery
,
surgery
Saturday, February 05, 2011
abstract: Indication for oophorectomy during cytoreduction for intraperitoneal metastatic spread of colorectal or appendiceal origin
BACKGROUND: The incidence of ovarian metastases at the time of peritoneal carcinomatosis, and the influence of such metastases on survival after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), are unknown.
CONCLUSION: When peritoneal carcinomatosis of colorectal or appendiceal origin is confirmed, at least 52 per cent of ovaries will have synchronous metastases. Disease-free survival after a HIPEC procedure for PMCA or DPAM is significantly lower in women with ovarian metastases. Oophorectomy during CRS for peritoneal carcinomatosis should be strongly considered.
add your opinions
appendiceal
,
appendix
,
colorectal
,
oophorectomy
Friday, August 20, 2010
Compliance with estrogen hormone replacement therapy after oophorectomy: a prospective study -- Menopause International
Results. The median age of women at the time of hysterectomy was 42 (range 22–46) years
add your opinions
compliance
,
hormone replacement therapy
,
HRT
,
hysterectomy
,
menopause
,
oophorectomy
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