OVARIAN CANCER and US: pathologic response

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Showing posts with label pathologic response. Show all posts
Showing posts with label pathologic response. Show all posts

Wednesday, January 25, 2012

Studies Reignite Debate over Avastin (Bevacizumab) in Breast Cancer - in Oncology/Hematology, Breast Cancer from MedPage Today



Action Points

  • These two studies found a benefit in the surrogate endpoint of complete pathologic response with the addition of bevacizumab in neoadjuvant treatment for HER2-negative breast cancer.


  • Note that pathologic complete response was defined differently in the two studies -- in the breast and nodes in one and only in the breast in the other; applying the more stringent breast-plus-nodes criterion in the second study eliminated the statistical significance.